Holistic therapy for slimming and obesity

ID: 50

Pack Weight: 50 tea bags

Price: 56 $        

Pharmaceutical Form: Herbal MEDICAL Mixtures

ingredients:

1. Hibiscus sabdariffata.
2. Cola acuminata.
3. Fucus vermiculosis.
4. Cassia angustifolia.
5. Spina rest harrow.
 The phytokinetics of this creational formula interacts in ways that enhance and magnify the remedy elements content in the sub ingredients (synergetic effect) with out any out control side effects.
 This formula represents a complete therapy protocol in simple phytoceutical form and over advanced in phytokinetics.

This formula:
- This formula and (Herbs in general) contain some compounds with low-molecular weight and highly lipophilic compounds easily diffuse across cell membranes to induce biological reactions which shall lead to the homeostasis.
- This formula contain some herbs classified among plants “generally recognized as safe (GRAS)” by the FDA- US. And consider as safe herbs by PDR (physician desk reference) USA, and commission e/ Germany.
- All these herbs contain flavonoids.
- Phytochemicals in this formula control hunger and thirst through save potential mechanistically on thalamus and hypothalamus.
- These herbs had been used in the alimentary regimen for many populations all over the world hundreds or thousands years ago and still the must important source of remedy and other similar usage.

phytochemical and phytokinetics:

Important consideration:
It's well known that the source of estrogen mimickers to day are many: polluted air, polluted water, detergents, paints, plastic, some processed foods and more other.. (For example see the abstract, no. 1). And so all men and women alike are exposed to estrogenic chemicals day after day known as xenoestrogenes. Xenoestrogenes are capable of mimicking estrogen activity in the human body. The ongoing assaults of these chemicals affect the body like excesse estrogens.. This shall lead to wide alteration such as metabolism disturbances (over weight and obesity) and human breast cancer cell …..
- University of western Ontario, London Canada. Control the breast cancer by inhibiting the proliferation of estrogen receptors-posetive MCF-7 human breast cancer cells through some flavonoids (see the enclosed abstract).
- Ibnalnafis herb company adopts this mechanism in controlling the overweight and obesity/ {The genistein is mildly estrogenic. (PDR) page: 762- 3TH edition}.

The main study
1. Hibiscus sabdariffa:
- It's biological acknowledged that the subepidermic papillary plexuses consider an important factor in the temperature homeostasis locally (in the skin) and in general for the whole human organism.
This formula contain hibiscus sabdariffa classified as cooling herb by southern university USA h. Hibiscus sabdariffa increase blood flow to the skin's surface and dilating the pores to cool the skin gently and safely, this process increase the dermic lipid catabolism in order to maintain thermodermal homeostasis and as a sequence the sub coetaneous fat (cellulite) shall be removed.
In addition h. sabdariffa drain the retention water in the interstitial medium [European Food Safety Authority (EFSA)] which consider the other hand of the over weight, and has the ability to increase urination, attributed to two diuretic ingredients, ascorbic acid and glycolic acid, (southern university USA).
H. sabdariffa also changes in bowel function within the normal range e.g. reduce transit time, increase frequency of bowel movements or bulk of stools might be interpreted as improvement of bowel motor function. (European food safety authority)
- Correction of the intestinal function control the abdominal flatulence, accumulation and fermentation of the faeces in the intestine, and reduce the intestinal transit time.
- H. sabdariffa are used for loosing of appetite. (PDR)
- H. sabdariffa tea has a laxative effect due to the high content of poorly absorbable fruit acid. (PDR)
- H. sabdariffa had been used as slimming agent source in many pharmaceutical forms creams, capsules, tea bags and other ...by many international herbal firms world wide.
- Side effects and adverse reactions of H. sabdariffa: health risks or side effects following the proper administration of designated therapeutic dosage are not recorded. (PDR)

2. Also this formula contain the energizing plant cola acuminate which contain two alkaloids, caffeine [biological acknowledge caffeine is a natural calorie burner].
and theobromine, which are powerful stimulants that counteract fatigue, suppress thirst and hunger (modulate the food behavior), and are believed to enhance intellectual activity (PDR- Nickalls, 1986; Sundstrom, 1966).
- Cola nuts are also used as a source of alkaloids in pharmaceutical preparations (Opeke, 1992).
- Cola acuminata has mild positive chronotropic effect (increase slightly the heart rate).
[Oxford forestry institute, department of plant sciences, university of oxford UK].
- Cola acuminata approved by commition e for lack of stamina. (PDR)
- Cola acuminata consider analeptic herb. (PDR), an analeptic: is a restorative, or remedies proper to restore the body, when wasted or emaciated by disease or hunger.
- Side effects and adverse reactions of cola acuminata: use of cola is contraindicated during pregnancy. The herb should not administer in the presence of stomach or duodenal ulcers due to the herb stimulation of gastric juice secretion (PDR).

3. Cassia angustifolia (senna):
Cassia angustifolia belong to the stimulant laxatives. The mode of action is based on two mechanisms. Firstly, colonic motility is increased leading to a reduced transit time and reduced fluid absorption. Secondly, an influence on secretion processes by two concomitant mechanisms, namely inhibition of absorption of water and electrolytes (Na,Cl) into the colonic epithelial cells (antiabsorptive effect) and increase of the leakiness of the tight junctions and stimulation of secretion of water and electrolytes into the lumen of the colon (secretagogue effect), results in enhanced concentrations of fluid and electrolytes in the lumen of the colon.
- Side effects and adverse reactions of cassia angustifolia:
Chronic use or abuse of Cassia angustifolia may lead to hypokalaemia. This hypokalaemia and the increased loss of potassium may increase the activity of cardiac glycosides and interfere with the action of antiarrythmic agents.
[European Medicines Agency- Evaluation of Medicines for Human Use: London, 27 April 2007].
- This herb is contraindicated in intestinal obstruction, acute inflammatory intestinal diseases or appendicitis. Not to be used during pregnancy and nursing. (PDR)

4- Spiny rest harrow:
- Spinal rest harrow in combination with sufficient liquid intake the drug said to be diuretic. (PDR)
- The genistein {is isoflavone (estrogen-like substance found in plants)} is mildly estrogenic. PDR
- Estrogens play an important role in a variety of aspects of physiology, estrogen receptors are mechanistically implicated in endocrine-related diseases. Recent studies with estrogen receptor unravel the role of the estrogen receptors in brain degeneration, osteoporosis, cardiovascular diseases and obesity.
Merck KGaA, Institute of Toxicology, 64271 Darmstadt, Germany.
Laboratory of Reproductive and Developmental Toxicology- USA
- It's well known that Genistein is one of several known isoflavones. Isoflavones, are found in a number of plants, many isoflavones have been shown to interact in safely mode with human estrogen receptors and control the xenoestrogen (and other Endocrine disruptor) causing modulating effect/ return to the homeostasis parameters/ in the human body (mal and female) , and as its likely known this processes shall control the estrogen balance and the balance of estrogen with other hormones such as:
Estrogen ------------------ progesterone balance in female.
Estrogen ------------------ testosterone balance in male……
And as a sequence right metabolic environment within the body shall control the over weight and obesity.
- Contraindications:
The drug should not be used in the presence of edema resulting from reduced cardiac or renal activity. PDR
5. Fucus vesiculosus:
Fucus vesiculosus:
Antilipidemic: Fucus vesiculosus polysaccharides were shown to interfere with hepatic synthesis of low- density liporprotein (LDL) cholesterol and triglycerides and increase high- density lipoprotein (HDL) cholesterol level in hyperlipidemic animal laboratory (PDR).
- It's biological acknowledge that aqua's infusion of polysaccharides (carbohydrates) limits the absorption of lipids from the intestinal wall.
- Aqua's infusion of polysaccharides gives the feeling of satisfaction, support and regulates the biological functions (see the abstract no. 5).
- Hypoglycemic effects, anti- inflammatory.
- Indications: for obesity and over weight.
- Contra indications:
Fucus vesiculosus is contraindicated in hyperthyroidism, pregnancy and in breast feeding mothers. PDR

In the end:
the synergetic remarkable effect of this formula and due to the limited herbal researches in the international level can't be well evaluated through the actual medical literature.

administration:

middle spoon , or tea bag from the mixture to a glass of boiled water /capacity of 200 ml. ( boiled previously) then cover it for ten minutes, filter it and have it half an hour before the meal. 2-3 times daily.
Prophylactically: once daily.

useful combination:

I. In case of local fat deposition in legs and hips use the:
- formula no. 30.
- The cream no. 216.
- The soap no. 317.
II. - Its advisable to share your treatment with the "nafis royal venigar" 217 due to its positive effect on the metabolism of glucids and lipids, and due to some: vitamins, minerals, and fibers which support the general state of the human organism during diet. For more details see the "nafis royal venigar" page.
- In un responding cases it's preferable to add the formula no. 57 "nafis herbavit" to your therapy due to its vit. B6 and B12 content (…. Among overweight or obese men and women, long-term use of multivitamins, vitamins B6 and B12, were significantly associated with lower levels of weight gain.
(Fred Hutchinson Cancer Research Center, Seattle, Washington).
(Bastyr University Research Institute, Kenmore, Washington).

The Science Behind our Perfect Formulae:
Ibnalnafis Herb Company perform clinical trials compliance to GMP standards and criteria and under the surveillance of seventy medicines specialist in deferent disciplines over many clinics distributed in Syria and some Arab countries in addition to turkey.

Every formula produced commercially must be passed at least through clinical trial stage 1(to see if an experimental medication or treatment is safe. After a treatment is tested in the lab or on animals, it enters a phase 1 clinical trial that is done with humans. A phase 1 clinical trial usually involves only a small number of people to determine if a drug or treatment is safe and to determine the best dose).

All our formula was screened in very clever way based on:
- Old manuscript of Arabic medicine for: the big medical practitioner in the meddle ages ibnalnafis, and for Avicenna and more others.
- Recent western researcher.
- PDR, physician desk reference (the American guide for medicinal herbs).
- FDA, USA and their herbal screening.
R&D department